Lab News
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The Adams Lab received a Pilot Research Grant from the National Multiple Sclerosis Society!This award is helping us generate new data to understand how sterol signaling contributes to myelin repair in MS.
January 2019 |
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Dharma and Zita's paper is published in Cell Chemical Biology!"Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP" Cell Chemical Biology, 2019, https://doi.org/10.1016/j.chembiol.2019.01.004
14 February 2019 |
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Welcome Matthew!Matthew Pleshinger has joined the lab as a graduate student in the department of pharmacology!
December 2018 |
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Dharma departs the Adams lab to establish the Dharmaraja Lab at IITK!We are thrilled to announce that Dharma has accepted a faculty position at Indian Institute of Technology Kanpur in the department of Chemistry! Best of luck to Dharma!
November 2018 |
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Zita wins first place for her oral presentation at the Biomedical Graduate Student Symposium
25 October 2018 |
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Zita and Dharma's paper is published in Nature!"Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination" Nature, 2018, http://dx.doi.org/10.1038/s41586-018-0360-3
Our work provides a new roadmap for promoting myelin repair in multiple sclerosis and other diseases. Huge thanks to everyone who helped us out along the way, whether across the hall (that's you, Tesar Lab) or across the globe! Check out the press release for more info: http://casemed.case.edu/cwrumed360/news-releases/release.cfm?news_id=1375&news_category=8 25 July 2018 |
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Drew and Paul co-found Convelo Therapeutics!Convelo Therapeutics, Inc. disclosed today that it has raised $7.8 million to develop new therapeutics for diseases of myelin. Co-founded by Drew and close collaborator Paul Tesar, Convelo is located in Cleveland and led by a team of Boston-based biotech pioneers: CEO Derrick Rossi (co-founder of Moderna, Intellia, and Magenta) and Chief Development Officer Steve Landau (Shape, Tensha).
Check out the press release for more details! https://www.businesswire.com/news/home/20180725005491/en/Convelo-Therapeutics-Develop-New-Regenerative-Medicines-Neurological 25 July 2018 |
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Drew is now the Thomas F. Peterson, Jr. Professor of Cancer and Energy Research!At a ceremony led by Dean Davis, Drew was honored as the Thomas F. Peterson, Jr. Professor of Cancer and Energy Research. Tom's generous support has accelerated the research of several Case Western Reserve scientists, including two endowed chairs, and it was a pleasure to have him join the ceremony. Thanks Tom!
28 June 2018 |
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Zita wins Ruth L. Kirschstein NRSA F30 Fellowship!Zita Hubler was awarded an individual research fellowship for her work investigating the mechanism of action of small molecules which enhance oligodendrocyte formation. This fellowship will provide her with funding to enhance her training as a future physician-scientist.
7 June 2018 |
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Drew wins the CWRU Jackson Award for undergraduate mentoringCase Western Reserve University President Barbara Snyder visited the Genetics Department today to honor Drew with the J. Bruce Jackson, MD Award for Excellence in Undergraduate Mentoring. A very cool honor for a junior faculty member -- nice apple, too!
"The Jackson Award celebrates two faculty annually who have guided a student in their academic and career paths; fostered the student’s long-term personal development; challenged the student to reflect, explore and grow as an individual; and supported and/or facilitated the student’s goals and life choices." 1 May 2018 |
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Matt is awarded an ACS Organic Division SURF Fellowship!Following close on the heels of his Goldwater Scholarship, Matt Thompson has now been awarded a competitive fellowship from the American Chemical Society to support his research this summer. Amazing! Drew claims he won the same fellowship as an undergrad, but it must've pre-dated the internet because we can't find any record of it...
5 April 2018 |
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Matt wins the Goldwater Scholarship!Wow! Matt won a Goldwater Scholarship! "The most prestigious undergraduate scholarship in the natural sciences, mathematics, and engineering in America." A truly well-deserved honor. We've posted the goofiest picture available to keep you humble.
4 March 2018 |
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Welcome Farrah!Farrah Gao has joined the lab as an undergraduate researcher - welcome!
4 March 2018 |
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Welcome Joel!Joel Sax has committed to joining the lab for the PhD phase of his MD/PhD training. Joel previously did chemical biology research as an undergraduate at UC-Berkeley. Welcome Joel!
26 Feb 2018 |
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Ryan joins the lab!Ryan is joining the lab as a postdoctoral fellow and will work closely with the Small Molecule Drug Development Core. He completed his PhD at the University of Iowa in organic chemistry.
14 Feb 2018 |
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Dharma’s paper published in ACS Chemical Biology!This work identified a protein disulfide isomerase (PDI) targeting covalent chemical probe featuring a novel 2-choloroproipionamide electrophile, and this probe is the least reactive irreversible inhibitor of PDI reported to date.
14 June 2017 |